With over 15 years of IHC testing history, our experience in immunohistochemistry has been developed and solidified through service provided to multiple hospital systems across the country.

The use of automation in the IHC process results in:

  • Improved slides
    Greater consistency and quality of the slides.
  • Increased optimization
    Better optimization of antibody performance through enhanced protocols.
  • Quicker processing
    Continuous loading system allows for the immediate processing of STAT cases at any time during the IHC work flow cycle.

Processed IHC slides (TC) can be provided to clients by mail or digitally scanned for immediate review. In addition, online consultation is available with our pathologists through Applied Diagnostics’ online imaging platform.


IHC/IHS test offering

PanelsDisease Indication
Breast Cancer CD34, Cytokeratin 5/6, EGFR, ER, GCDFP-15, GFAP, HER2/Neu, Ki67, Mammoglobin, p53 Nuclear Antigen, PR
Epithelial Alpha-Fetoprotein (AFP), Cal-Retinin, CAM 5.2, CD15, CDX2, CEA (Carcinoembryonic Antigen), Cytokeratin 19, Cytokeratin 20, Cytokeratin 5/6, Cytokeratin 7, Cytokeratin-HMW (CK-903), E-Cadherin, EGFR, EMA (Epithelial Membrane Antigen), HEPAR I, MOC-31, p63, PLAP (Placental Alkaline Phosphatase), PSA (Prostate Specific Antigen), PSAP (Prostate Specific Acid Phosphatase)
Genitourinary CA125, CEA, CK20, Cytokeratin 7, Inhibin, PR, PR, WT1
Gastrointestinal CA19-9, CDX2, CEA, Cytokeratin 14, Cytokeratin 19, Cytokeratin 20, Cytokeratin 7, p53
Infectious Agents CMV Helicobacter Pylori, HHV8, HSV I/II, Human Papilloma Virus (HPV)
Lung Cal-Retinin, CD56, NK Cell, Cytokeratin 5/6, TTF-1 (Thyroid Transcription Factor), Cytokeratin-Pan
Leukemia/Lymphoma ALK, ALK Protein (ALK-1), BCL-2 Oncoprotein, BCL6, CD10 (CALLA), CD138, CD15, CD1A, CD20, CD23, CD3, CD30, CD34, CD38, CD43, CD45 (LCA), CD5, CD56, CD57, CD68, Macrophage, CD79, CD8, Hemoglobin A, Kappa, PAX-5
Melanoma HMB45, MART-1, Melan A, S100, Vimentin
Mesenchymal CD117 (c-Kit), CD34, CD99, Desmin, SMA (Smooth Muscle Actin), SMM (Smooth Muscle Myosin), Vimentin
Mesothelioma Cal-Retinin, Cytokeratin 5/6, WT1
Neural/Neuroendocrine Calcitonin, CD56, NK Cell, Chromogranin, NSE (Neuron Specific Enolase), Synaptophysin
Prostate Cancer Cytokeratin 5/6, Cytokeratin-HMW (Cytokeratin-903)-(Cytokeratin 34 beta E12), p63, PIN2 (Racemase, P63 - double stain), PSA (Prostate Specific Antigen), PSAP (Prostate Specific Acid Phosphatase), Racemase
Undifferentiated Tumor CD45 (LCA), Cytokeratin-Pan, S100, SMA (Smooth Muscle Actin), Vimentin
Additional IHC Stains Ber-EP4, CD117, CD163, CD31, CD4, CEA polyclonal, Cyclin-D1, D2-40, Factor VIII, Factor XIII, Gastrin, HCG (Human Chorionic Gonadotropin), MART 1/Ki67 (double stain), MART 1/Melan A (Fast Red), MPO, MUM-1, P-Cadherin, RCC (Renal Cell Carcinoma), TdT, Thyroglobulin, ZAP-70

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