Applied Diagnostics’ tests and methodologies include:
Flow Cytometry, which uses laser-beam technology to analyze and characterize cells. Flow Cytometry is used in the diagnosis and evaluation of prognosis of cancers. It is particularly useful in the diagnosis and prognosis of lymphomas and leukemias.
Immunohistochemistry (IHC), the basic tool of molecular pathology. IHC is a type of assay in which specific cellular antigens are detected by the use of labeled antibodies.
Fluorescence In Situ Hybridization (FISH), a technique that uses fluorescent-labeled DNA probes to detect a particular chromosome or gene.
Chromogenic In Situ Hybridization (CISH), an emerging technology for the detection of gene or chromosome changes using DNA probes requiring only light microscopy. Technology similar to FISH, employing chromogenic detection instead of fluorescent probes.
Quantitative Image Analysis, which involves the processing and analysis of visual information produced in biological microscopy.
Circulating Tumor Cells (CTC), to monitor patient clinical status at any time during chemotherapy. CTC is critical in tumor monitoring, for evaluation of progression and response to chemotherapy of metastatic breast, colorectal, and prostate cancers.