Applied Diagnostics’ tests and methodologies include:
Flow Cytometry, which uses a laser-powered instrument to measure the amount of DNA in cells. Flow Cytometry is used in the diagnosis and evaluation of prognosis of certain cancers. It is particularly useful in the diagnosis and prognosis of lymphomas and leukemias.
Immunohistochemistry (IHC), the basic tool of molecular pathology. IHC is a type of assay in which specific cellular antigens are detected by the use of specifically dyed antibodies.
Fluorescence In Situ Hybridization (FISH), a technique that uses fluorescent-labeled DNA probes to detect a particular chromosome or gene.
Chromogenic In Situ Hybridization (CISH), an emerging technology for the detection of DNA probes using specific dyes and requiring only light microscopy. Technology similar to FISH by using specific chromogens instead of fluorescent dyes.
Quantitative Image Analysis involves the processing and analysis of visual information produced in immunochemical microscopy.
Circulating Tumor Cells (CTC), to monitor patient clinical status at any time during chemotherapy. CTC is critical in tumor monitoring, for evaluation of progression and response to chemotherapy of metastatic breast, colorectal, and prostate cancers.
